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Article

Cryptic and polar variation of the fragile X repeat could result in predisposing normal alleles.

Cell - 17 Jun 1994

Kunst C B, Warren S T

Abstract excerpt

Fragile X syndrome results from the expansion of a CGG repeat that is normally interrupted by occasional AGG triplets. Linkage disequilibrium suggests that certain normal haplotypes may contribute unequally to the pool of fragile X chromosomes. Sequence analysis of normal alleles demonstrates haplotype-specific variation of the cryptic nature of the repeat. Variation occurs principally at the 3' end of the...

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Source

Identifiers

PMID: 7911740
DOI: 10.1016/0092-8674(94)90134-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cryptic and polar variation of the fragile X repeat could result in predisposing normal alleles.PMID 7911740Read ↗

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