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Article

Insert size and flanking haplotype in fragile X and normal populations: possible multiple origins for the fragile X mutation.

Human molecular genetics - 1 Mar 1994

Macpherson J N, Bullman H, Youings S A, Jacobs P A

Abstract excerpt

A number of recent studies have found non-random association between the fragile X mutation and genotypes for the closest-linked flanking markers, suggesting either a limited number of 'founder' mutations or, alternatively, a predisposing haplotype for the fragile X expansions. Using three microsatellite markers within 150 kb of FRAXA, we have compared haplotypes in a series of fragile X males and in a control...

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Identifiers

PMID: 8012351
DOI: 10.1093/hmg/3.3.399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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