A novel HLA haplotype containing a DRB5 gene associated with the DRB1*0103 allele.

doi:10.1111/j.1399-0039.1993.tb02197.x

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Article

A novel HLA haplotype containing a DRB5 gene associated with the DRB1*0103 allele.

Tissue antigens - 1 Nov 1993

Perrier P, Leotard B, Henry M A

Abstract excerpt

A new hybrid haplotype, a DRB1*0103 allele associated with a DRB5*0101 allele, was found in a French Caucasoid family and has been described here. When these cells were typed by serology, contrarily to cells with the DR1 + 2s haplotype, they did not seem to be triplets. The reactivity of these cells with the DR2 allosera led to a false serological HLA-DR typing. RFLP analysis and DNA oligotyping after DR1-DRB1,...

Topics

Alleles
Female
HLA Antigens
HLA-DR Antigens
HLA-DRB1 Chains
HLA-DRB5 Chains
Haplotypes
Histocompatibility Antigens Class II
Humans
Male
Nucleic Acid Hybridization
Pedigree

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

White People

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