Lack of HLA-DR2-associated DRB1 gene in a family.

doi:10.1111/j.1399-0039.1997.tb02842.x

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Article

Lack of HLA-DR2-associated DRB1 gene in a family.

Tissue antigens - 1 Jul 1997

Singal D P, Ye M, Joseph S

Abstract excerpt

HLA-DR51 haplotypes co-express one DRB1 (B1*15 or B1*16) gene and one DRB5 gene. These haplotypes also carry two pseudogenes (DRB6 and DRB9) During routine HLA typing for transplantation, we observed an unexpected DR51 haplotype in two subjects (mother and daughter) in a family. Serological typin...

Topics

Female
Genetic Variation
HLA-DR Antigens
HLA-DR2 Antigen
HLA-DRB1 Chains
Haplotypes
Histocompatibility Testing
Humans
Kidney Transplantation
Male
Polymerase Chain Reaction

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