Article
A novel HLA-haplotype containing a DRB5 gene not associated with DRB1*15 or DRB1*16 alleles.
Tissue antigens - 1 Feb 1992
Tautz C, Marsh D G, Baur X
Abstract excerpt
In Caucasians, HLA-DR2 haplotypes usually express two DRB genes encoding the DR specificity. The DRB5 genes are in strong linkage disequilibrium with the respective DRB1*15 or DRB1*16 alleles. So far, no other DRB1 alleles have been found in association with DRB5 genes. Here, we report evidence for a probably recombinant DRB5 haplotype with a DRB1 allele not specific for DR2. From our results the haplotype...
Topics
- Adult
- Alleles
- Base Sequence
- HLA Antigens
- HLA-DR Antigens
- HLA-DRB1 Chains
- HLA-DRB5 Chains
- Haplotypes
- Histocompatibility Antigens Class II
- Humans
- Male
- Molecular Sequence Data
