Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RFLP analysis of HLA-DR5 haplotypes.

Tissue antigens - 1 Feb 1991

Reed E, McManus P, Suciu-Foca N

Abstract excerpt

The analysis of HLA-DR5 haplotypes unravelled a new DRB3 polymorphism and permitted the identification of various associations between alleles of the DRB1 and DRB3 loci. This new polymorphism consists of a 10.5 kb Taq1 restriction fragment which was encountered in an African-American family (JS). In Caucasoids, the DRw11 allele has been previously observed only in association with the DRw52b allele. RFLP and...

Topics

Alleles
Base Sequence
Genes, MHC Class II
HLA-DR5 Antigen
Haplotypes
Humans
Molecular Sequence Data
Polymorphism, Restriction Fragment Length
Racial Groups

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1676191
DOI: 10.1111/j.1399-0039.1991.tb01847.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1676191-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RFLP analysis of HLA-DR5 haplotypes.PMID 1676191Read ↗

Rapid DNA typing for class II HLA antigens: subtyping of DRw52-associated DRB1 alleles.Semantic proximity Read ↗

Comprehensive typing of DR52 (DRB3)-associated DRB1 and DRB3 alleles by PCR-RFLP.Semantic proximity Read ↗

HLA-DRB5 genotyping by PCR-RFLP.Semantic proximity Read ↗

HLA-DR2-associated DRB1 and DRB5 alleles and haplotypes in Koreans.Semantic proximity Read ↗

DNA typing for class II HLA antigens with allele-specific or group-specific amplification. II. Typing for alleles of the DRw52-associated group.Semantic proximity Read ↗

Polymorphism of HLA-DRw52-associated DRB1 genes as defined by sequence-specific oligonucleotide probe hybridization and sequencing.Semantic proximity Read ↗

A three-step allele-level DRB1-DRB3-DRB4-DRB5 genotyping assay using polymerase chain reaction with immobilized sequence-specific oligoprobes.Semantic proximity Read ↗

Oligonucleotide typing analysis for the linkage disequilibrium between the polymorphic DRB1 and DRB5 loci in DR2 haplotypes.Semantic proximity Read ↗

HLA-DRw52-associated DRB1 alleles: identification using polymerase chain reaction-amplified DNA, sequence-specific oligonucleotide probes, and a chemiluminescent detection system.Semantic proximity Read ↗

Complete analysis of HLA-DQB1 polymorphism and DR-DQ linkage disequilibrium by oligonucleotide typing.Semantic proximity Read ↗

Direct sequencing of SSP-PCR-amplified cDNA to identify new alleles in the DR52-associated DRB1 group: identification of DRB1*1115, DRB1*1117 and DRB1*1319.Semantic proximity Read ↗

Polymorphism of DRw52 and its association with DRw11 and DRw12 in South African blacks (Negroes) and individuals of mixed ancestry (Cape coloreds).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.