Article
Diversity and virulence thresholds in AIDS.
Proceedings of the National Academy of Sciences of the United States of America - 18 Jan 1994
de Boer R J, Boerlijst M C
Abstract excerpt
We propose a model for the interaction between human immunodeficiency virus and the immune system. Two differential equations describe the interactions between one strain of virus and one clone of T lymphocytes. We use the model to generalize earlier results pertaining to the AIDS diversity thres...
Topics
- Acquired Immunodeficiency Syndrome
- Antigenic Variation
- CD4-Positive T-Lymphocytes
- Clone Cells
- HIV
- Humans
- Models, Biological
- Mutation
- Virulence