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Article

Diversity and virulence thresholds in AIDS.

Proceedings of the National Academy of Sciences of the United States of America - 18 Jan 1994

de Boer R J, Boerlijst M C

Abstract excerpt

We propose a model for the interaction between human immunodeficiency virus and the immune system. Two differential equations describe the interactions between one strain of virus and one clone of T lymphocytes. We use the model to generalize earlier results pertaining to the AIDS diversity threshold [Nowak, M. A., Anderson, R. M., McLean, A. R., Wolfs, T. F. W., Goudsmit, J. and May, R. M. (1991) Science 254,...

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Identifiers

PMID: 7904755
DOI: 10.1073/pnas.91.2.544
PMCID: PMC42985

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