Article
Population dynamics of immune responses to persistent viruses.
Science (New York, N.Y.) - 5 Apr 1996
Nowak M A, Bangham C R
Abstract excerpt
Mathematical models, which are based on a firm understanding of biological interactions, can provide nonintuitive insights into the dynamics of host responses to infectious agents and can suggest new avenues for experimentation. Here, a simple mathematical approach is developed to explore the rel...
Topics
- Antibodies, Viral
- Antigenic Variation
- Antigens, Viral
- Cytokines
- Cytotoxicity, Immunologic
- Epitopes
- Genetic Variation
- HIV Infections
- HIV-1
- HTLV-I Infections
- Human T-lymphotropic virus 1
- Humans
- Models, Biological
- Mutation
- Population Dynamics
- T-Lymphocytes, Cytotoxic
- Virus Diseases
- Virus Physiological Phenomena