Article
Lack of association between immunoglobulin light-chain constant- and variable-region polymorphisms (C kappa, V kappa II, V lambda VII and VHIII) and rheumatoid arthritis.
Experimental and clinical immunogenetics - 1 Jan 1993
Sidebottom D, Bate A S, Grennan D M
Abstract excerpt
Restriction fragment length polymorphisms (RFLPs) of C kappa, V kappa II, V lambda VII and VHIII genes were studied from a pool of 104 subjects with rheumatoid arthritis and 96 controls. There were no overall associations with either rheumatoid arthritis itself, or with HLA-DR4-positive and DR4-n...
Topics
- Alleles
- Arthritis, Rheumatoid
- Genes, Immunoglobulin
- Humans
- Immunoglobulin Variable Region
- Immunoglobulin kappa-Chains
- Immunoglobulin lambda-Chains
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length