Lack of association between immunoglobulin light-chain constant- and variable-region polymorphisms (C kappa, V kappa II, V lambda VII and VHIII) and rheumatoid arthritis.

Abstract excerpt

Restriction fragment length polymorphisms (RFLPs) of C kappa, V kappa II, V lambda VII and VHIII genes were studied from a pool of 104 subjects with rheumatoid arthritis and 96 controls. There were no overall associations with either rheumatoid arthritis itself, or with HLA-DR4-positive and DR4-negative RA subgroups within rheumatoid subjects in this UK Caucasoid population.

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