Article
DNA variants of alpha-1-antitrypsin in rheumatoid arthritis with and without pulmonary complications.
Disease markers - 1 Jan 2000
Bate A S, Sidebottom D, Cooper R G, Loftus M, Chattopadhyay C, Grennan D M
Abstract excerpt
Restriction fragment length polymorphisms (RFLPs) of alpha-1-antitrypsin were studied in 99 subjects with rheumatoid arthritis alone, 21 subjects with rheumatoid arthritis and pulmonary fibrosis, 26 subjects with rheumatoid arthritis and bronchiectasis, and 86 controls. No associations with either rheumatoid arthritis itself or with the associated pulmonary disorders were noted in this U.K. Caucasoid population.
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