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Article

Polymorphism of HSP70 gene is not associated with type 1 (insulin-dependent) diabetes mellitus in Japanese.

Diabetes research and clinical practice - 1 Jan 2000

Kawaguchi Y, Ikegami H, Fukuda M, Fujioka Y, Shima K, Ogihara T

Abstract excerpt

Heat shock protein (HSP) 70 is one of the stress-induced proteins and a candidate for islet autoantigen of Type 1 (insulin-dependent) diabetes mellitus. Association of PstI-8.5 kb allele of HSP70 gene with Type 1 diabetes was previously reported in the Caucasian population. Since HSP70 gene is located in the class III region of HLA, the association may be due to the linkage disequilibrium between class II HLA and...

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PMID: 7903628
DOI: 10.1016/0168-8227(93)90056-b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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