Article
Failure to find evidence for linkage or association between the dopamine D3 receptor gene and schizophrenia.
The American journal of psychiatry - 1 Jan 1994
Sabaté O, Campion D, d'Amato T, Martres M P, Sokoloff P, Giros B, Leboyer M, Jay M, Guedj F, Thibaut F
Abstract excerpt
OBJECTIVE: This study was performed to assess the possible involvement of the dopamine D3 receptor gene (DRD3) in the etiology of schizophrenia. The authors' approach included a population study and a family study using both parametric (lod score) and nonparametric (affected pedigree member) meth...
Topics
- Alleles
- Ethnicity
- Family
- Female
- Genetic Linkage
- Humans
- Lod Score
- Male
- Models, Genetic
- Pedigree
- Phenotype
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Psychotic Disorders
- Receptors, Dopamine
- Schizophrenia
- Schizotypal Personality Disorder
