Article
Failure to find evidence for linkage or association between the dopamine D3 receptor gene and schizophrenia.
The American journal of psychiatry - 1 Jan 1994
Sabaté O, Campion D, d'Amato T, Martres M P, Sokoloff P, Giros B, Leboyer M, Jay M, Guedj F, Thibaut F
Abstract excerpt
OBJECTIVE: This study was performed to assess the possible involvement of the dopamine D3 receptor gene (DRD3) in the etiology of schizophrenia. The authors' approach included a population study and a family study using both parametric (lod score) and nonparametric (affected pedigree member) methods of linkage analysis. METHOD: Two different DNA markers were studied at the DRD3 locus. The family study included 35...
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