Fetal hematopoietic stem cell transplantation into beta-thalassemic mice.

doi:10.1016/s0022-3468(05)80304-5

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Article

Fetal hematopoietic stem cell transplantation into beta-thalassemic mice.

Journal of pediatric surgery - 1 Oct 1993

Bethel C A, Muragesh D, Harrison M R, Mohandas N, Rubin E R

Abstract excerpt

The transplantation of fetal-derived hematopoietic stem cells (HSCs) may potentially be used to treat hemoglobinopathies, immunodeficiencies, and storage diseases. The levels of donor cell engraftment needed to reconstitute the recipient's hematopoietic system are disease-dependent and remain unk...

Topics

Animals
Animals, Newborn
Blood Protein Electrophoresis
Chimera
Fetal Tissue Transplantation
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells
Hemoglobins
Liver
Liver Transplantation
Mice
Mice, Inbred C57BL
Phenotype
Time Factors
Transplantation, Isogeneic
beta-Thalassemia

Source

Open in PubMed

Identifiers

PMID: 7903357
DOI: 10.1016/s0022-3468(05)80304-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7903357-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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