Article
Rapid and Complete Donor Chimerism after Unrelated Mismatched Cord Blood Transplantation in 5 Children with β-Thalassemia Major
21 Apr 2005
Abstract excerpt
Hematopoietic stem cell transplantation is currently the only curative therapy for beta-thalassemia major. However, <30% of patients have unaffected HLA-identical siblings to serve as donors. We investigated the feasibility of using umbilical cord blood transplants from unrelated HLA mismatched donors and a myeloablative preparative regimen that did not involve total body irradiation. Between October 2003 and...
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