Article
The dominant mutation Suppressor of black indicates that de novo pyrimidine biosynthesis is involved in the Drosophila tan pigmentation pathway.
Molecular & general genetics : MGG - 1 Nov 1993
Piskur J, Kolbak D, Søndergaard L, Pedersen M B
Abstract excerpt
A deficiency in the production of beta-alanine causes the black (b) phenotype of Drosophila melanogaster. This phenotype is normalized by a semi-dominant mutant gene Su(b) shown previously to be located adjacent to or within the rudimentary (r) locus. The r gene codes for three enzyme activities...
Topics
- Animals
- Aspartate Carbamoyltransferase
- Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)
- Color
- Dihydroorotase
- Drosophila
- Female
- Genes, Dominant
- Male
- Phenotype
- Pyrimidines
- Suppression, Genetic