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Article

Drosophila tan encodes a novel hydrolase required in pigmentation and vision.

PLoS genetics - 1 Nov 2005

True John R, Yeh Shu-Dan, Hovemann Bernhard T, Kemme Tobias, Meinertzhagen Ian A, Edwards Tara N, Liou Shian-Ren, Han Qian, Li Jianyong

Abstract excerpt

Many proteins are used repeatedly in development, but usually the function of the protein is similar in the different contexts. Here we report that the classical Drosophila melanogaster locus tan encodes a novel enzyme required for two very different cellular functions: hydrolysis of N-beta-alanyl dopamine (NBAD) to dopamine during cuticular melanization, and hydrolysis of carcinine to histamine in the metabolism...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16299587
DOI: 10.1371/journal.pgen.0010063
PMCID: PMC1285064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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