Article
An avaII restriction fragment length polymorphism in the insulin-like growth factor II gene and the occurrence of smooth muscle tumors.
Cancer research - 1 Dec 1993
Gloudemans T, Pospiech I, Van der Ven L T, Lips C J, Den Otter W, Sussenbach J S
Abstract excerpt
To detect a previously described AvaII restriction fragment length polymorphism (RFLP) in the human insulin-like growth factor II (IGF-II) gene we used the polymerase chain reaction (PCR) and genomic sequencing. The RFLP is located in exon 9 of the IGF-II gene at nucleotide 820 (GenBank accession...
Topics
- Alleles
- Base Sequence
- Female
- Gene Frequency
- Humans
- Insulin-Like Growth Factor II
- Leiomyoma
- Leiomyosarcoma
- Male
- Molecular Sequence Data
- Muscular Diseases
- Polymerase Chain Reaction