Article
[Gene diagnosis of hemophilia B by multiple STR analysis].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Mar 2002
Liu Xiangfan, Wang Xuefeng, Fan Qishi, Chu Haiyan, Fang Yi, Wang Hongli
Abstract excerpt
OBJECTIVE: To establish a simple, rapid genetic diagnostic system for haemophilia B. METHODS: The polymorphisms of eight STR loci in 87 normal persons and 8 haemophilia B families were assayed by PCR and genescan, and the linkage relations were analysed. RESULTS: Six of the eight STR loci can provide genetic information for haemophilia B, and the heterozygosity is 0.50 approximately 0.83, PIC 0.39 approximately...
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