Article
A rapid multifluorescent polymerase chain reaction for genetic counselling in Chinese haemophilia A families.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jan 2006
Fang Y, Wang X-F, Dai J, Wang H-L
Abstract excerpt
Linkage analysis is a widely used strategy for genetic counselling in haemophilia A (HA) families. We attempted to develop more informative markers closely linked to factor VIII (FVIII) gene and establish a rapid multifluorescent polymerase chain reaction (PCR) method with these markers. Five extragenic (DXS15, DXS9901, G6PD, DXS1073 and DXS1108) and one intragenic (F8Civs13) markers were examined in 118 healthy...
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