Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Telomeric and nontelomeric (TTAGGG)n sequences in gene amplification and chromosome stability.

Genomics - 1 Nov 1994

Bertoni L, Attolini C, Tessera L, Mucciolo E, Giulotto E

Abstract excerpt

We have isolated eight PALA-resistant mutants from CHO-PV cells and have shown that the CAD gene was amplified. We then localized the CAD genes with fluorescence in situ hybridization followed by G-banding and identified 10 different marker chromosomes carrying amplified DNA. TTAGGG repetitions, which normally map to the telomeres and centromeres, have also been localized on the 10 marker chromosomes. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to CHO Cells
Share to Cricetinae

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Drug Resistance

Share to Fibroblasts

Share to Gene Amplification

Share to Mutation

Source

Identifiers

PMID: 7896289
DOI: 10.1006/geno.1994.1581

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Telomeric and nontelomeric (TTAGGG)n sequences in gene amplification and chromosome stability.PMID 7896289Read ↗

Late onset of CAD gene amplification in unamplified PALA resistant Chinese hamster mutants.Semantic proximity Read ↗

Genetic characterization of CHO production host DG44 and derivative recombinant cell lines.Semantic proximity Read ↗

Loss of alleles in aprt mutants of CHO cells demonstrated by BclI restriction-fragment-length variation.Semantic proximity Read ↗

The evolution of the amplified adenylate deaminase 2 domains in Chinese hamster cells suggests the sequential operation of different mechanisms of DNA amplification.Semantic proximity Read ↗

Molecular analysis of a novel subtelomeric repeat with polymorphic chromosomal distribution.Semantic proximity Read ↗

From Chromosomes to Precision Therapy: Clinical Cytogenetics and Cytogenomics in the Era of Genomic MedicineSemantic proximity Read ↗

Complex chromosomal mechanisms lead to APRT loss of heterozygosity in heteroploid cells.Semantic proximity Read ↗

Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.