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Article

Further examples of evolution by gene duplication revealed through DNA sequence comparisons.

Genetics - 1 Dec 1994

Ohta T

Abstract excerpt

To test the theory that evolution by gene duplication occurs as a result of positive Darwinian selection that accompanies the acceleration of mutant substitutions, DNA sequences of recent duplication were analyzed by estimating the numbers of synonymous and nonsynonymous substitutions. For the troponin C family, at the period of differentiation of the fast and slow isoforms, amino acid substitutions were shown to...

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Identifiers

PMID: 7896112
DOI: 10.1093/genetics/138.4.1331
PMCID: PMC1206269

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