Article
Mechanisms of mutation formation with long-wave ultraviolet light (UVA).
Photodermatology, photoimmunology & photomedicine - 1 Feb 2008
Rünger Thomas M, Kappes Ulrike P
Abstract excerpt
Long-wave ultraviolet (UV) A light is able to damage DNA, to cause mutations, and to induce skin cancer, but the exact mechanisms of UVA-induced mutation formation remain a matter of debate. While pyrimidine dimers are well established to mediate mutation formation with shortwave UVB, other types of DNA damage, such as oxidative base damage, have long been thought to be the premutagenic lesions for UVA...
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