Article
The yeast magmas ortholog pam16 has an essential function in fermentative growth that involves sphingolipid metabolism.
PloS one - 1 Jan 2012
Short Mary K, Hallett Joshua P, Tar Krisztina, Dange Thomas, Schmidt Marion, Moir Robyn, Willis Ian M, Jubinsky Paul T
Abstract excerpt
Magmas is a growth factor responsive gene encoding an essential mitochondrial protein in mammalian cells. Pam16, the Magmas ortholog in Saccharomyces cerevisiae, is a component of the presequence translocase-associated motor. A temperature-sensitive allele (pam16-I61N) was used to query an array of non-essential gene-deletion strains for synthetic genetic interactions. The pam16-I61N mutation at ambient...
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