Article
A variation in the apolipoprotein C-III gene is associated with an increased number of circulating VLDL and IDL particles in familial combined hyperlipidemia.
Journal of lipid research - 1 Jun 1997
Ribalta J, La Ville A E, Vallvé J C, Humphries S, Turner P R, Masana L
Abstract excerpt
Detailed plasma lipoprotein analyses were conducted on 16 familial combined hyperlipidemic (FCHL) probands, all their available family members (n = 106) together with 12 normolipidemic control families (n = 68), and the results were assessed in relation to a C1100-T polymorphism in exon 3 of the apoC-III gene. The frequency of the T1100 genotype (CT+TT) was significantly elevated in the probands relative to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
