Article
A variation in the apolipoprotein C-III gene is associated with an increased number of circulating VLDL and IDL particles in familial combined hyperlipidemia.
Journal of lipid research - 1 Jun 1997
Ribalta J, La Ville A E, Vallvé J C, Humphries S, Turner P R, Masana L
Abstract excerpt
Detailed plasma lipoprotein analyses were conducted on 16 familial combined hyperlipidemic (FCHL) probands, all their available family members (n = 106) together with 12 normolipidemic control families (n = 68), and the results were assessed in relation to a C1100-T polymorphism in exon 3 of the...
Topics
- Adolescent
- Adult
- Alleles
- Apolipoprotein A-I
- Apolipoprotein C-III
- Apolipoproteins
- Apolipoproteins C
- Base Sequence
- Cholesterol
- DNA Primers
- Female
- Gene Frequency
- Genotype
- Humans
- Hyperlipidemia, Familial Combined
- Lipoproteins
- Lipoproteins, IDL
- Lipoproteins, VLDL