Article
Elevated neuronal c-Fos-like immunoreactivity and messenger ribonucleic acid (mRNA) in genetically obese (ob/ob) mice.
Brain research - 12 Dec 1994
Mistry A M, Helferich W, Romsos D R
Abstract excerpt
Adult genetically obese (ob/ob) mice display a number of metabolic alterations, the primary cause of which may be a defect in their central nervous system (CNS). The protein encoded by the protooncogene c-fos, c-Fos, functions as a nuclear transcription factor, and also serves as a marker of neur...
Topics
- Animals
- Arcuate Nucleus of Hypothalamus
- Blotting, Northern
- Brain Chemistry
- Food Deprivation
- Gene Expression
- Genes, fos
- Immunohistochemistry
- Male
- Mice
- Mice, Obese
- Neurons
- Neuropeptide Y
- Obesity
- Paraventricular Hypothalamic Nucleus
- Phenotype
- RNA, Messenger