Article
Sequences in the preC region of duck hepatitis B virus affect pregenomic RNA accumulation.
Virology - 10 Mar 1995
Chang C, Hirsch R C, Ganem D
Abstract excerpt
The pregenomic RNA of hepadnaviruses serves as both the mRNA for the core and polymerase proteins and the RNA template for reverse transcription. We have identified a region in the duck hepatitis B virus pregenomic RNA transcription unit that is critical for the accumulation of this transcript. This 85-nt region, termed alpha, is located within the preC region; deletion of alpha results in drastically reduced...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
