Evidence for a major gene affecting postchallenge insulin levels in Mexican-Americans.

doi:10.2337/diab.44.3.284

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Article

Evidence for a major gene affecting postchallenge insulin levels in Mexican-Americans.

Diabetes - 1 Mar 1995

Mitchell B D, Kammerer C M, Hixson J E, Atwood L D, Hackleman S, Blangero J, Haffner S M, Stern M P, MacCluer J W

Abstract excerpt

Hyperinsulinemia, which is considered a hallmark of insulin resistance, precedes the development of non-insulin-dependent diabetes mellitus (NIDDM). Results of family and twin studies have shown that heredity influences insulin resistance and insulin levels. In Caucasian families ascertained thro...

Topics

Adult
Age Factors
Alleles
Base Sequence
DNA
DNA Primers
Diabetes Mellitus, Type 2
Female
Genetic Carrier Screening
Genetic Linkage
Genetic Markers
Glucose Tolerance Test
Humans
Insulin
Insulin Resistance
Lymphocytes
Male
Mexican Americans

Source

Open in PubMed

Identifiers

PMID: 7883115
DOI: 10.2337/diab.44.3.284

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7883115-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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