Article
Evidence for a major gene affecting postchallenge insulin levels in Mexican-Americans.
Diabetes - 1 Mar 1995
Mitchell B D, Kammerer C M, Hixson J E, Atwood L D, Hackleman S, Blangero J, Haffner S M, Stern M P, MacCluer J W
Abstract excerpt
Hyperinsulinemia, which is considered a hallmark of insulin resistance, precedes the development of non-insulin-dependent diabetes mellitus (NIDDM). Results of family and twin studies have shown that heredity influences insulin resistance and insulin levels. In Caucasian families ascertained through two or more NIDDM siblings, it has been reported that single genes with large effects, i.e., major genes, influence...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.