Article
Sideroblastic anaemia.
Bailliere's clinical haematology - 1 Dec 1994
May A, Fitzsimons E
Abstract excerpt
The startling morphological abnormalities of sideroblastic anaemia contrasts our uncertainty about its cause. Studies are hampered by the fact that the abnormality resides in the dividing and differentiating erythroblast which is difficult to obtain pure and in large numbers, and in which many levels of metabolic control must coexist. Recent molecular biology approaches have confirmed abnormalities of erythroid...
Topics
- 5-Aminolevulinate Synthetase
- Anemia, Sideroblastic
- Biological Transport
- Chloramphenicol
- Copper
- DNA, Mitochondrial
- Erythrocytes
- Ferrochelatase
- Genetic Linkage
- Globins
- Heme
- Humans