Article
Causes and Pathophysiology of Acquired Sideroblastic Anemia.
Genes - 30 Aug 2022
Rodriguez-Sevilla Juan Jose, Calvo Xavier, Arenillas Leonor
Abstract excerpt
The sideroblastic anemias are a heterogeneous group of inherited and acquired disorders characterized by anemia and the presence of ring sideroblasts in the bone marrow. Ring sideroblasts are abnormal erythroblasts with iron-loaded mitochondria that are visualized by Prussian blue staining as a perinuclear ring of green-blue granules. The mechanisms that lead to the ring sideroblast formation are heterogeneous,...
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