Article
The temperature-sensitive mutants of Toxoplasma gondii and ocular toxoplasmosis.
Vaccine - 22 Jan 2009
Lu Fangli, Huang Shiguang, Kasper Lloyd H
Abstract excerpt
The risk of blindness caused by ocular toxoplasmosis supports efforts to improve our understanding for control of this disease. In this study, the involvement of CD8(+), CD4(+), B cell, and IL-10 gene in the immune response of primary ocular infection with the temperature-sensitive mutant (ts-4) of the RH Toxoplasma gondii strain, and in the protective immunity of ocular ts-4 vaccination and challenge with RH...
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