Article
Phenotypic characterisation of a Neospora caninum temperature-sensitive strain in normal and immunodeficient mice.
International journal for parasitology - 1 Oct 1999
Dreier K J, Stewarter L W, Kerlin R L, Ritter D M, Brake D A
Abstract excerpt
The in vivo persistence, immunogenicity and pathogenicity of a recently described temperature-sensitive (ts) strain from Neospora caninum, NCts-8, was investigated in normal and immunodeficient mice. Groups of BALB/c and SCID/Bg mice were infected s.c. with 5 x 10(6) wild-type NC-1, control NCts-8 (pass 0) or NCts-8 tachyzoites prepared at four in vitro passage levels (pass 7, 13, 21 and 28). For persistence and...
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