Article
Cell cycle regulation of the p34cdc2/p33cdk2-activating kinase p40MO15.
Journal of cell science - 1 Oct 1994
Poon R Y, Yamashita K, Howell M, Ershler M A, Belyavsky A, Hunt T
Abstract excerpt
A key component of Cdc2/Cdk2-activating kinase (CAK) is p40MO15, a protein kinase subunit that phosphorylates the T161/T160 residues of p34cdc2/p33cdk2. The level and activity of p40MO15 were essentially constant during cleavage of fertilised Xenopus eggs and in growing mouse 3T3 cells, but serum starvation of these cells reduced both the level and activity of p40MO15. Although the level and activity of...
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