Article
N-glycan-dependent quality control of the Na,K-ATPase beta(2) subunit.
Biochemistry - 13 Apr 2010
Tokhtaeva Elmira, Munson Keith, Sachs George, Vagin Olga
Abstract excerpt
Bulky hydrophilic N-glycans stabilize the proper tertiary structure of glycoproteins. In addition, N-glycans comprise the binding sites for the endoplasmic reticulum (ER)-resident lectins that assist correct folding of newly synthesized glycoproteins. To reveal the role of N-glycans in maturation...
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