Article
The scoliosis (sco) mouse: a new allele of Pax1.
Cytogenetic and genome research - 1 Jan 2005
Adham I M, Gille M, Gamel A J, Reis A, Dressel R, Steding G, Brand-Saberi B, Engel W
Abstract excerpt
We describe the spontaneous mutant mouse scoliosis (sco) that carries a new allele of Pax1 (un-i, undulated intermediate). The Pax1(un-i) allele is lacking the 5'-flanking region and exon 1 to 4 which is mapped to nt -2636 to -640 and -272 to 4271 of the Pax1 gene. Homozygous mice show a mild form of the known phenotypes of other Pax1 mutants. Adult mice have a lumbar scoliosis and kinky tails. In homozygous...
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