Article
The regulation of hedgehog and decapentaplegic during Drosophila eye imaginal disc development.
Mechanisms of development - 1 Aug 1996
Strutt D I, Mlodzik M
Abstract excerpt
The hedgehog signalling pathway is a conserved mechanism which acts in inductive processes in both vertebrate and invertebrate development to direct growth and patterning. In Drosophila, the secreted Hedgehog protein acts as a signal to induce non-autonomous activation in adjacent cells of either the decapentaplegic or wingless genes (both of which encode growth factor-like molecules), via inactivation of patched...
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