Article
Primary structure and function of a second essential member of the heterooligomeric TCP1 chaperonin complex of yeast, TCP1 beta.
Proceedings of the National Academy of Sciences of the United States of America - 29 Mar 1994
Miklos D, Caplan S, Mertens D, Hynes G, Pitluk Z, Kashi Y, Harrison-Lavoie K, Stevenson S, Brown C, Barrell B
Abstract excerpt
A role for heterooligomeric TCP1 complex as a chaperonin in the eukaryotic cytosol has recently been suggested both by structural similarities with other chaperonins and by in vitro experiments showing it to mediate ATP-dependent folding of actin, tubulin, and luciferase. Here we present the prim...
Topics
- Alleles
- Amino Acid Sequence
- Cell Division
- Chaperonin Containing TCP-1
- Chaperonins
- Fluorescent Antibody Technique
- Genes, Fungal
- Genome, Fungal
- Molecular Sequence Data
- Mutagenesis
- Phenotype
- Protein Conformation
- Proteins
- Saccharomyces cerevisiae