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Article

Inheritance of immunoglobulin subclass regulator-1 (Igsr-1) in LEC mutant rats.

The Journal of veterinary medical science - 1 Oct 1994

Sakai T, Agui T, Miura M, Yamada T, Matsumoto K

Abstract excerpt

Long-Evans Cinnamon (LEC) mutant rats were reported to exhibit a deficiency in the serum immunoglobulin (Ig) G1. The phenotype determining the basal level of IgG1 was tentatively designated as immunoglobulin subclass regulator-1 (Igsr-1), and normal rats and LEC rats were categorized into Igsr-1A (normal expression of IgG1) and Igsr-1B (low expression of IgG1), respectively. In this report we examined genetic...

Topics

Animals
CD4-Positive T-Lymphocytes
Crosses, Genetic
Enzyme-Linked Immunosorbent Assay
Female
Flow Cytometry
Immunoglobulin G
Immunologic Deficiency Syndromes
Male
Phenotype
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats, Mutant Strains

Reference Values

T-Lymphocytes, Helper-Inducer

Source

Identifiers

PMID: 7865588
DOI: 10.1292/jvms.56.883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7865588-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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