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Article

Homozygosity mapping of the Werner syndrome locus (WRN).

Genomics - 1 Oct 1994

Nakura J, Wijsman E M, Miki T, Kamino K, Yu C E, Oshima J, Fukuchi K, Weber J L, Piussan C, Melaragno M I

Abstract excerpt

Werner syndrome (WS) is an autosomal recessive disorder characterized by the early onset of several age-related diseases. The locus for this disease was recently mapped to 8p12. We studied 27 WS kindreds of mixed ethnic origins, 26 of which were consanguineous. In 24 of these families, the affected subject was given the diagnosis of "definite" WS and affected subjects in the remaining 3 pedigrees were given the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 7851888
DOI: 10.1006/geno.1994.1548

Genes

WRN
PLAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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