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Recent Trends in WRN Gene Mutation Patterns in Individuals with Werner Syndrome.

Journal of the American Geriatrics Society - 1 Aug 2017

Yamaga Masaya, Takemoto Minoru, Takada-Watanabe Aki, Koizumi Naoko, Kitamoto Takumi, Sakamoto Kenichi, Ishikawa Takahiro, Koshizaka Masaya, Maezawa Yoshiro, Yokote Koutaro

Abstract excerpt

OBJECTIVES: To determine recent trends in mutation patterns in the WRN gene, which cause Werner syndrome (WS), a rare, inheritable progeroid syndrome in Japan. DESIGN: Retrospective cohort. SETTING: Longitudinal survey of WS and literature search for case reports. PARTICIPANTS: Individuals whose genetic testing their facilities had requested between 2009 and October 2016 (N = 67). MEASUREMENTS: A nationwide...

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PMID: 28394436
DOI: 10.1111/jgs.14906

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WRN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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