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Article

Polyamine toxicity in Neurospora crassa: protective role of the vacuole.

Archives of biochemistry and biophysics - 1 Mar 1991

Davis R H, Ristow J L

Abstract excerpt

We used mutant strains of Neurospora crassa to define the discretionary capacity of this species for excess putrescine. The spe-3 mutant, which accumulates putrescine internally, and the puu-1 mutant, which accumulates toxic levels of putrescine from the medium, both sequestered large excesses of putrescine in vacuoles. Concomitantly in puu-1, inorganic polyphosphate increased modestly and some of the monovalent...

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Identifiers

PMID: 1832828
DOI: 10.1016/0003-9861(91)90364-o

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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