Article
Adenovirus E1A expression controlled by the red pigment promoter in transgenic mice: a model for developmental abnormalities of the eye.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Oct 1994
Wang Y, Albert D M, Shenk T
Abstract excerpt
Four transgenic founder mice were produced that carry the adenovirus E1A gene under control of the human red pigment promoter. Two of the founder animals passed the transgene to progeny, and one line was bred to homozygosity. The line of mice homozygous for the transgene expressed E1A-specific RN...
Topics
- Adenovirus E1A Proteins
- Animals
- Disease Models, Animal
- Eye Abnormalities
- Gene Expression Regulation, Developmental
- Gene Expression Regulation, Viral
- Mastadenovirus
- Mice
- Mice, Transgenic
- Phenotype
- Pigment Epithelium of Eye
- Promoter Regions, Genetic