Mutagenicity studies of benzalazine.

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Article

Mutagenicity studies of benzalazine.

Arzneimittel-Forschung - 1 Dec 1994

Herzog R, Leuschner J

Abstract excerpt

Benzalazine (2-hydroxy-5-[(4-carboxyphenyl) azo] benzoic acid, CAS 64896-26-0), a new agent for the treatment of ulcerative colitis and Crohn's disease of the large intestine, was studied for genotoxic effects by using the following short-term in vitro and in vivo test: 1. reverse mutation test (Ames method) on Salmonella typhimurium, 2. HGPRT (hypoxanthine-guanine phosphoribosyl transferase) point mutation test...

Topics

Animals
Benzaldehydes
Cell Line
Cricetinae
Cricetulus
Female
Hydrazones
Hypoxanthine Phosphoribosyltransferase
In Vitro Techniques
Male
Metaphase
Mutagenicity Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagens

Mutation

Point Mutation

Rats

Rats, Inbred Strains

Salmonella typhimurium

Source

Open in PubMed

Identifiers

PMID: 7848359

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7848359-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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