A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1 alpha polymorphism.

doi:10.1002/art.1780380210

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Article

A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1 alpha polymorphism.

Arthritis and rheumatism - 1 Feb 1995

McDowell T L, Symons J A, Ploski R, Førre O, Duff G W

Abstract excerpt

OBJECTIVE: The genetic factors that predispose to the development of juvenile rheumatoid arthritis (JRA) and its complications are not completely understood. The cytokine interleukin-1 (IL-1) has been implicated in the pathogenesis of JRA and other inflammatory diseases. This study was performed...

Topics

Adult
Alleles
Arthritis, Juvenile
Arthritis, Rheumatoid
Base Sequence
Blood Sedimentation
Gene Frequency
Humans
Interleukin-1
Iridocyclitis
Molecular Sequence Data
Norway
Polymorphism, Genetic

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