Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1 alpha polymorphism.

Arthritis and rheumatism - 1 Feb 1995

McDowell T L, Symons J A, Ploski R, Førre O, Duff G W

Abstract excerpt

OBJECTIVE: The genetic factors that predispose to the development of juvenile rheumatoid arthritis (JRA) and its complications are not completely understood. The cytokine interleukin-1 (IL-1) has been implicated in the pathogenesis of JRA and other inflammatory diseases. This study was performed to test whether polymorphisms of the IL-1 alpha gene might be associated with JRA. METHODS: We sequenced the 5'...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Arthritis, Rheumatoid
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Interleukin-1

Share to Molecular Sequence Data

Share to Norway

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 7848312
DOI: 10.1002/art.1780380210

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1 alpha polymorphism.PMID 7848312Read ↗

Association of single nucleotide polymorphisms within cytokine genes with juvenile idiopathic arthritis in the Czech population.Semantic proximity Read ↗

Cytokine gene polymorphisms and susceptibility to juvenile idiopathic arthritis. British Paediatric Rheumatology Study Group.Semantic proximity Read ↗

Genetic epidemiology of juvenile idiopathic arthritisSemantic proximity Read ↗

Genetics of juvenile idiopathic arthritis: an update.Semantic proximity Read ↗

TNF-alpha promoter gene polymorphisms in Spanish children with persistent oligoarticular and systemic-onset juvenile idiopathic arthritis.Semantic proximity Read ↗

Association of interleukin-1 family gene polymorphisms with juvenile idiopathic arthritis in Iranian population.Semantic proximity Read ↗

The interleukin-1 beta 511C>T polymorphism is associated with susceptibility to juvenile idiopathic arthritis in a Turkish population.Semantic proximity Read ↗

Association of interleukin-2 and interferon-γ single nucleotide polymorphisms with Juvenile systemic lupus erythematosus.Semantic proximity Read ↗

Association of IL-10 gene polymorphisms and susceptibility to Juvenile Idiopathic Arthritis in Egyptian children and adolescents: a case-control study.Semantic proximity Read ↗

TNF-alpha 863C > A promoter and TNFRII 196T > G exonic variationsmay be risk factors for juvenile idiopathic arthritisSemantic proximity Read ↗

Interleukin-6, interleukin-1 gene cluster and interleukin-1 receptor polymorphisms in Iranian patients with juvenile systemic lupus erythematosus.Semantic proximity Read ↗

Association of RANTES promoter polymorphism with juvenile rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.