Article
Methods for genetic linkage analysis using trisomies.
American journal of human genetics - 1 Feb 1995
Feingold E, Lamb N E, Sherman S L
Abstract excerpt
Certain genetic disorders are rare in the general population, but more common in individuals with specific trisomies. Examples of this include leukemia and duodenal atresia in trisomy 21. This paper presents a linkage analysis method for using trisomic individuals to map genes for such traits. It...
Topics
- Chromosome Mapping
- Diploidy
- Genetic Linkage
- Genetic Markers
- Genotype
- Homozygote
- Humans
- Models, Genetic
- Statistics as Topic
- Trisomy