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Article

Methods for genetic linkage analysis using trisomies.

American journal of human genetics - 1 Feb 1995

Feingold E, Lamb N E, Sherman S L

Abstract excerpt

Certain genetic disorders are rare in the general population, but more common in individuals with specific trisomies. Examples of this include leukemia and duodenal atresia in trisomy 21. This paper presents a linkage analysis method for using trisomic individuals to map genes for such traits. It is based on a very general gene-specific dosage model that posits that the trait is caused by specific effects of...

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Identifiers

PMID: 7847384
PMCID: PMC1801125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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