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Article

Karyomapping: a universal method for genome wide analysis of genetic disease based on mapping crossovers between parental haplotypes.

Journal of medical genetics - 1 Oct 2010

Handyside Alan H, Harton Gary L, Mariani Brian, Thornhill Alan R, Affara Nabeel, Shaw Marie-Anne, Griffin Darren K

Abstract excerpt

The use of genome wide single nucleotide polymorphism (SNP) arrays for high resolution molecular cytogenetic analysis using a combination of quantitative and genotype analysis is well established. This study demonstrates that by Mendelian analysis of the SNP genotypes of the parents and a sibling or other appropriate family member to establish phase, it is possible to identify informative loci for each of the...

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Source

Identifiers

PMID: 19858130
DOI: 10.1136/jmg.2009.069971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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