Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Parvovirus B19 Nonstructural (NS1) Protein Induces Apoptosis in Erythroid Lineage Cells

1 Apr 1998

Abstract excerpt

Infection of erythroid-lineage cells by human parvovirus B19 is characterized by a gradual cytocidal effect. Accumulating evidence now implicates the nonstructural (NS1) protein of the virus in cytotoxicity, but the mechanism underlying the NS1-induced cell death is not known. Using a stringent regulatory system, we demonstrate that NS1 cytotoxicity is closely related to apoptosis, as evidenced by cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatological and COVID-19 studies
Share to Parvovirus B19 Infection Studies

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9525624
DOI: 10.1128/jvi.72.4.3018-3028.1998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Parvovirus B19 Nonstructural (NS1) Protein Induces Apoptosis in Erythroid Lineage CellsPMID 9525624Read ↗

Parvovirus Infection-Induced Cell Death and Cell Cycle ArrestSemantic proximity Read ↗

Parvovirus B19 Nonstructural Protein-Induced Damage of Cellular DNA and Resultant ApoptosisSemantic proximity Read ↗

Parvovirus B19 and the pathogenesis of anaemiaSemantic proximity Read ↗

Human parvovirus B19 DNA replication induces a DNA damage response that is dispensable for cell cycle arrest at phase G2/M.Semantic proximity Read ↗

Conserved Cysteine-Rich Domain of Paramyxovirus Simian Virus 5 V Protein Plays an Important Role in Blocking ApoptosisSemantic proximity Read ↗

Induction of Programmed Cell Death by Parvovirus H-1 in U937 Cells: Connection with the Tumor Necrosis Factor Alpha Signalling PathwaySemantic proximity Read ↗

Increased expression and secretion of interleukin-6 in human parvovirus B19 non-structural protein (NS1) transfected COS-7 epithelial cellsSemantic proximity Read ↗

Advances in human B19 erythrovirus biology.Semantic proximity Read ↗

The bovine viral diarrhea virus (BVDV) NS3 protein, when expressed alone in mammalian cells, induces apoptosis which correlates with caspase-8 and caspase-9 activation.Semantic proximity Read ↗

Human parvovirus B19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E2F family of transcription factorsSemantic proximity Read ↗

Human Parvovirus B19 Nonstructural Protein (NS1) Induces Cell Cycle Arrest at G 1 PhaseSemantic proximity Read ↗

Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.