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Article

Linkage disequilibrium of HLA-DR3 and HLA-DR4 with HLA-B alleles in Mexican patients with rheumatoid arthritis.

Clinical and experimental rheumatology - 1 Jan 2000

Avila-Portillo L M, Vargas-Alarcón G, Andrade F, Alarcón-Segovia D, Granados J

Abstract excerpt

OBJECTIVE: We studied the gene frequencies of classes I, II and III antigens of the Major Histocompatibility Complex (MHC) in 32 Mexican mestizo patients with rheumatoid arthritis (RA) and compared them with those obtained from 110 of their first degree relatives and 100 Mexican mestizo controls. Furthermore, we analyzed the observed and expected frequencies of the haplotypes and calculated the delta values in...

Topics

Alleles
Arthritis, Rheumatoid
Female
Gene Frequency
Genetic Linkage
HLA-B Antigens
HLA-DR3 Antigen
HLA-DR4 Antigen
Haplotypes
Humans
Major Histocompatibility Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mexico

Reference Values

Source

Identifiers

PMID: 7842529

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7842529-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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