Article
HLA-B alleles and complotypes in Mexican patients with seronegative spondyloarthropathies.
Annals of the rheumatic diseases - 1 Nov 1994
Vargas-Alarcón G, Garcia A, Bahena S, Melin-Aldana H, Andrade F, Ibañez-de-Kasep G, Alcocer-Varela J, Alarcón-Segovia D, Granados J
Abstract excerpt
OBJECTIVES: To analyse major histocompatibility complex (MHC) haplotypes in Mexican mestizo patients with seronegative spondyloarthropathies (SSpA) and normal controls, to discover if there are other antigens, besides B27, in the HLA region that might show association with the disease. METHODS: The study included 100 Mexican mestizo patients with SSpA and 200 of their first degree relatives. These groups were...
Topics
- Adult
- Alleles
- Arthritis, Reactive
- Complement C2
- Complement C4
- Complement Factor B
- Complement System Proteins
- Disease Susceptibility
- Female
- HLA-B Antigens
- HLA-B27 Antigen
