Article
Association of Human Leukocyte Antigen (HLA) class II (DRB1 and DQB1) alleles and haplotypes with Rheumatoid Arthritis in Sudanese patients.
Frontiers in immunology - 1 Jan 2023
Ali Adil Ahmed, Khalid Khalid Eltahir, Mohammed Somaya Elhaj, Akhtar Mohammed Salman, Saeed Osman Khalafalla
Abstract excerpt
The aim of this study was to determine the Human Leukocyte Antigen (HLA) class II (DRB1 and DQB1) alleles and haplotype frequency in Rheumatoid Arthritis (RA) in the Sudanese population. The frequency of HLA-DRB1 and -DQB1 alleles and DRB1-DQB1 haplotypes were determined in 122 RA patients and 100 controls. HLA alleles were genotyped by the polymerase chain reaction-sequence specific primers (PCR-SSP) method. In...
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