Article
Potential of avian and mammalian species A rotaviruses to reassort as explored by plasmid only-based reverse genetics.
Virus research - 1 Sept 2020
Patzina-Mehling Corinna, Falkenhagen Alexander, Trojnar Eva, Gadicherla Ashish K, Johne Reimar
Abstract excerpt
Species A rotavirus (RVA) is an important gastrointestinal pathogen that is widely distributed in humans, mammalian animals and birds. The RVA genome consists of eleven double-stranded RNA segments, enabling the generation of novel strains with new pathogenic or antigenic features by genetic reassortment. While reassortants between human and mammalian animal RVAs have been repeatedly described, data on the...
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